Study Finds Collagen-Producing Cells Heal Patients Faster Than Only Plasma for Tendinopathy

Orthopedic Sports Medicine

Ultrasound-guided injection of autologous skin-derived tendon-like cells can be used to treat patellar tendinopathy with greater improvement in pain and function than with plasma alone for short-term use, according to an article published in The American Journal of Sports Medicine.

Researchers took a four-millimeter skin biopsy from 46 patients with refractory patellar tendinopathy to grow tendocyte-like collagen-producing cells. Patients either received an injection with laboratory-prepared, amplified collagen-producing cells derived from dermal fibroblasts and suspended in autologus plasma or an injection with autologous plasma alone for treatment. The injections were made to the sites of the hypoechogenicity, intrasubstance tears and fibrillar discontinuity within the patellar tendon.

The patients who were treated with the collagen-producing cells had a significantly faster improvement than the group treated with only plasma.

Read the abstract for "Skin-Derived Tenocyte-like Cells for the Treatment of Patellar Tendinopathy."

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